Out with Microsoft products and in with open source!
Having bought the Linux eeePC a month or so back and having been using Firefox and OpenOffice for several years, I finally decided to go the whole hog and get rid of Microsoft Office, including Outlook. So I'm now running Thunderbird, Lightning and the OpenOffice suite. So far, the main difference I've noticed is that the computer starts up faster!
The main real difference, however, is that I can now keep everything synchronised between my computers.